As we go to press, the threat of biological or chemical warfare in the Persian Gulf is no longer imminent. Yet the questions raised by the proposed use of “investigational drugs,” without informed consent, to protect U.S. troops remain. The article by Edmund G. Howe and Edward D. Martin presents the arguments that informed the Pentagon's thinking on the subject. It and the commentaries, by George J. Annas and Michael A. Grodin, and Robert J. Levine, explore, among others, issues (...) of informed consent, of distinguishing ‘research’ and ‘treatment,’ and of the nature and extent of the autonomy of military personnel.—B‐JC, HLN. (shrink)

This is a book grounded in the real ethical challenges of modern business practice, with a world-religious perspective so necessary in an era of globalization.

Philosophical writing on the welfare state has taken a defensive turn in recent years, largely in response to two related phenomena: the re-emergence of pro-market ideologies in the larger political culture and the imperiled condition of real world welfare states in a global economy in which national governments have diminishing capacities for shaping the social and economic lives of their citizens. But thanks in part to the tireless advocacy of Philippe Van Parijs, an even more radically redistributive form of public (...) provision than the welfare state has come onto the intellectual agenda—and the political agenda too, at least in Belgium and the Netherlands. Van Parijs proposes that all citizens be accorded an unconditional “basic income grant” as large as is compatible with the need to generate as much wealth as possible for redistribution. By now, this idea has many defenders. It also boasts a genealogy extending back to such writers as Tom Paine, François Huet, Edward Bellamy and G. D. H. Cole. But Van Parijs has become its best-known and most adept philosophical proponent, and this book represents his most sustained effort to date to investigate its normative foundations. (shrink)

Philosophical writing on the welfare state has taken a defensive turn in recent years, largely in response to two related phenomena: the re-emergence of pro-market ideologies in the larger political culture and the imperiled condition of real world welfare states in a global economy in which national governments have diminishing capacities for shaping the social and economic lives of their citizens. But thanks in part to the tireless advocacy of Philippe Van Parijs, an even more radically redistributive form of public (...) provision than the welfare state has come onto the intellectual agenda—and the political agenda too, at least in Belgium and the Netherlands. Van Parijs proposes that all citizens be accorded an unconditional “basic income grant” as large as is compatible with the need to generate as much wealth as possible for redistribution. By now, this idea has many defenders. It also boasts a genealogy extending back to such writers as Tom Paine, François Huet, Edward Bellamy and G. D. H. Cole. But Van Parijs has become its best-known and most adept philosophical proponent, and this book represents his most sustained effort to date to investigate its normative foundations. (shrink)

The observation that humans are often irrational has become commonplace. This observation has received empirical support from various experiments performed by cognitive scientists that are supposed to show that humans systematically violate principles of probability, rules of logic, and other norms of reasoning. In response to these experiments, philosophers have made creative and appealing arguments that these experiments must be mistaken or misinterpreted because humans must be rational. I examine these arguments for human rationality and show that they fail; cognitive (...) science does play a role in assessing human rationality. ;In Chapter One, I examine three cognitive science experiments in detail and discuss what is at issue in the debate about human rationality. At issue is whether the mistakes humans make are mere mistakes or indicative of systematic divergences from norms of reasoning. Defenders of human rationality say these mistakes are not characteristic of underlying reasoning abilities but are performance errors. Because humans make performance errors, human reasoning ability cannot be read off of behavior, but rather is to be studied by exploring cognitive competence, the underlying ability to reason. ;In Chapter Two, I develop and discuss the notion of cognitive competence. I then consider and reject two arguments that human cognitive competence must match the norms of reasoning. The first argument appeals to simplicity considerations, the second to the supposed common origin of our cognitive competence and our normative standards. In Chapter Three, I turn to a related argument for a view that humans are rational that says cognitive competence is discovered in the same way norms of reasoning are justified: both projects involve reflective equilibrium using as data people's judgments about what counts as good reasoning. ;In Chapter Four, I consider an argument for human rationality that draws on the principle of charity: when translating utterances of a speaker, one should try to interpret her utterances as rational and true. ;In Chapter Five, I consider an argument for human rationality that appeals to evolution. This argument claims that natural selection will select for cognitive mechanisms that produce true beliefs, and that such "truth-tropic" mechanisms are sufficient for being rational. ;My overall conclusion is that while cognitive science does not determine what the normative principles of reasoning are, it is relevant to whether or not human cognitive competence matches these principles; whether or not humans are irrational is, thus, an empirical question. (shrink)

I defend a naturalist theory of moral justification, "Confirmation Theory", from an objection raised by David Copp and Geoffrey Sayre-McCord. Confirmation Theory holds that some moral theory is justified because it is needed in the best empirical explanation of the world. The objection is that moral explanations are "incidental", that even if a moral theory is indispensable, this doesn't establish that any moral standard is justified. I show that the naturalist can concede that moral explanations are incidental and still maintain (...) the attractive elements of Confirmation Theory. (shrink)

The assembly of a bipolar spindle is essential for the accurate segregation of replicated chromosomes during cell division. Do chromosomes rely solely on other cellular components to regulate the assembly of the bipolar spindle or are they masters of their own fate? In the Zhang and Nicklas(1) study reviewed here, micromanipulation techniques and video microscopy were used to demonstrate the different roles that chromosome arms, kinetochores and centrosomes play in bipolar spindle assembly.

It was proposed that the data from Monte Carlo statistical investigations be subjected to analysis of variance methods rather than the conventional techniques of tabling, graphing, and inspecting the data. Two examples in which analysis of variance methods were applied to published Monte Carlo studies were presented. It was suggested that balanced factorial designs should be used whenever possible in Monte Carlo studies so that analysis of variance methods would be directly applicable. Finally, three advantages of analysis of variance methods (...) over conventional techniques were described and analysis of variance methods were contrasted with a possible alternative analytical method, multiple regression analysis. (shrink)